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1

Post-translational protein modifications in type 1 diabetes: a role for the repair enzyme protein-l-isoaspartate (d-aspartate)O-methyltransferase?

A. M. Wägner, P. Cloos, R. Bergholdt, P. Boissy, T. L. Andersen, D. B. Henriksen, C. Christiansen, S. Christgau, F. Pociot, J. Nerup

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 195 KB

english, 2007

2

Tumour Necrosis Factor-β Gene RFLP Alleles in Finnish IDDM Hapiotypes

J. ILONEN, H. MERIVUORI, H. REIJONEN, M. KNIP, H. K. ÅKERBLOM, F. POCIOT, J. NERUP, the Childhood Diabetes in Finland (DiMe) Study Group

Journal:

Scandinavian Journal of Immunology

Année:

1992

Langue:

english

Fichier:

PDF, 305 KB

english, 1992

3

A human phenome-interactome network of protein complexes implicated in genetic disorders

Lage, Kasper, Karlberg, E Olof, Størling, Zenia M, Ólason, Páll Í, Pedersen, Anders G, Rigina, Olga, Hinsby, Anders M, Tümer, Zeynep, Pociot, Flemming, Tommerup, Niels

Journal:

Nature Biotechnology

Année:

2007

Langue:

english

Fichier:

PDF, 767 KB

english, 2007

4

Neonatal levels of adiponectin, interleukin-10 and interleukin-12 are associated with the risk of developing type 1 diabetes in childhood and adolescence: A nationwide Danish case-control study

Thorsen, Steffen U., Pipper, Christian B., Eising, Stefanie, Skogstrand, Kristin, Hougaard, David M., Svensson, Jannet, Pociot, Flemming

Journal:

Clinical Immunology

Année:

2017

Langue:

english

Fichier:

PDF, 472 KB

english, 2017

5

GLP-1 Induces Barrier Protective Expression in Brunnerʼs Glands and Regulates Colonic Inflammation

Bang-Berthelsen, Claus H., Holm, Thomas L., Pyke, Charles, Simonsen, Lotte, Søkilde, Rolf, Pociot, Flemming, Heller, R. Scott, Folkersen, Lasse, Kvist, Peter H., Jackerott, Malene, Fleckner, Jan, Vili

Journal:

Inflammatory Bowel Diseases

Année:

2016

Langue:

english

Fichier:

PDF, 2.03 MB

english, 2016

6

Increased levels of inflammatory factors are associated with severity of polyneuropathy in type 1 diabetes

Okdahl, Tina, Brock, Christina, FlÃ¸yel, Tina, Wegeberg, AnneâMarie L, Jakobsen, Poul Erik, Ejskjaer, Niels, Pociot, Flemming, Brock, Birgitte, StÃ¸rling, Joachim

Journal:

Clinical Endocrinology

Année:

2020

Fichier:

PDF, 11.32 MB

2020

7

Genetic Variation of a Collagen IV α1-Chain Gene Polymorphism in Danish Insulin-dependent Diabetes Mellitus (IDDM) Patients: Lack of Association to Nephropathy and Proliferative Retinopathy

Chen, J.-W., Hansen, P.M., Tarnow, L., Hellgren, A., Deckert, T., Pociot, F.

Journal:

Diabetic Medicine

Année:

1997

Langue:

english

Fichier:

PDF, 123 KB

english, 1997

8

No linkage of P187S polymorphism in NAD(P)H: Quinone oxidoreductase (NQO1/DIA4) and type 1 diabetes in the Danish population

Ole P. Kristiansen, Zenia M. Larsen, Jesper Johannesen, Jørn Nerup, Thomas Mandrup-Poulsen, Flemming Pociot

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 144 KB

english, 1999

9

IDDM7 links to insulin-dependent diabetes mellitus in Danish multiplex families but linkage is not explained by novel polymorphisms in the candidate gene GALNT3

Ole P. Kristiansen, Flemming Pociot, Eric P. Bennett, Henrik Clausen, Jesper Johannesen, Jørn Nerup, Thomas Mandrup-Poulsen

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 37 KB

english, 2000

10

Combined genome and proteome approach to identify new susceptibility genes

Flemming Pociot, Allan E. Karlsen

Journal:

American Journal of Medical Genetics Part A

Année:

2002

Langue:

english

Fichier:

PDF, 194 KB

english, 2002

11

No evidence for SEL1L as a candidate gene for IDDM11-conferred susceptibility

Flemming Pociot, Zenia M. Larsen, Patrizia Zavattari, Elisabetta Deidda, Jørn Nerup, Monica Cattaneo, Raffaella Chiaramonte, Paola Comi, Marta Sabbadini, Massimo Zollo, Ida Biunno, Francesco Cucca

Journal:

Diabetes/Metabolism Research and Reviews

Année:

2001

Langue:

english

Fichier:

PDF, 65 KB

english, 2001

12

The relevance of international consortia in studies on the pathogenesis of type 1 diabetes: the role of ET1DGN

Flemming Pociot

Journal:

Diabetes/Metabolism Research and Reviews

Année:

2006

Langue:

english

Fichier:

PDF, 62 KB

english, 2006

13

Association of tumor necrosis factor (TNF) and class II major histocompatibility complex alleles with the secretion of TNF-a and TNF-0 by human mononuclear cells: a possible link to insulin-dependent diabetes mellitus

Flemming Pociot, Laurence Briant, C. Victor Jongeneel, Jens Mölvig, Helle Worsaae, Michel Abbal, Mogens Thomsen, Jørn Nerup, Anne Cambon-Thomsen

Journal:

European Journal of Immunology

Année:

1993

Langue:

english

Fichier:

PDF, 804 KB

english, 1993

14

No independent association between a tumor necrosis factor-α promotor region polymorphism and insulin-dependent diabetes mellitus

Flemming Pociot, Anthony G. Wilson, Jørn Nerup, Gordon W. Duff

Journal:

European Journal of Immunology

Année:

1993

Langue:

english

Fichier:

PDF, 458 KB

english, 1993

15

HLA associations in type 1 diabetes: DPB1 alleles may act as markers of other HLA-complex susceptibility genes

S. Johansson, B.A. Lie, F. Pociot, J. Nerup, A. Cambon-Thomsen, I. Kockum, E. Thorsby, D.E. Undlien

Journal:

Tissue Antigens

Année:

2003

Langue:

english

Fichier:

PDF, 99 KB

english, 2003

16

A population-based survey of frequencies of self-reported spontaneous and induced abortions in Danish women with Type 1 diabetes mellitus

T. Lorenzen, F. Pociot, J. Johannesen, O. P. Kristiansen, J. Nerup, The Danish IddM. Epidemiology, Genetics Group

Journal:

Diabetic Medicine

Année:

1999

Langue:

english

Fichier:

PDF, 127 KB

english, 1999

17

Evidence for linkage on chromosome 4p16.1 in Type 1 diabetes Danish families and complete mutation scanning of the WFS1 (Wolframin) gene

Z. M. Larsen, J. Johannesen, O. P. Kristiansen, J. Nerup, F. Pociot, The Danish IDDM Epidemiology, Genetics Group, The Danish Study Group of IDDM in Childhood

Journal:

Diabetic Medicine

Année:

2004

Langue:

english

Fichier:

PDF, 105 KB

english, 2004

18

Independent component and pathway-based analysis of miRNA-regulated gene expression in a model of type 1 diabetes

Claus H Bang-Berthelsen, Lykke Pedersen, Tina Fløyel, Peter H Hagedorn, Titus Gylvin, Flemming Pociot

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 798 KB

english, 2011

19

Further evidence that mutations inINScan be a rare cause of Maturity-Onset Diabetes of the Young (MODY)

Trine W Boesgaard, Stepanka Pruhova, Ehm A Andersson, Ondrej Cinek, Barbora Obermannova, Jeannet Lauenborg, Peter Damm, Regine Bergholdt, Flemming Pociot, Charlotta Pisinger, Fabrizio Barbetti, Jan Le

Journal:

BMC Medical Genetics

Année:

2010

Langue:

english

Fichier:

PDF, 275 KB

english, 2010

20

Zinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis?

Lærke Egefjord, Ledet Jens Jensen, Claus Heiner Bang-Berthelsen, Brønden Andreas Petersen, Kamille Smidt, Ole Schmitz, Allan Ertman Karlsen, Flemming Pociot, Fabrice Chimienti, Jørgen Rungby, Nils E M

Journal:

BMC Endocrine Disorders

Année:

2009

Langue:

english

Fichier:

PDF, 556 KB

english, 2009

21

Finding diabetic nephropathy biomarkers in the plasma peptidome by high-throughput magnetic bead processing and MALDI-TOF-MS analysis

Henning G. Hansen, Julie Overgaard, Maria Lajer, Frantisek Hubalek, Peter Højrup, Lykke Pedersen, Lise Tarnow, Peter Rossing, Flemming Pociot, James N. McGuire

Journal:

PROTEOMICS - Clinical Applications

Année:

2010

Langue:

english

Fichier:

PDF, 211 KB

english, 2010

22

Long-term risk of IDDM in first-degree relatives of patients with IDDM

T. Lorenzen, F. Pociot, P. Hougaard, J. Nerup

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 742 KB

english, 1994

23

A nationwide population-based study of the familial aggregation of Type 1 (insulin-dependent) diabetes mellitus in Denmark

F. Pociot, K. Nørgaard, N. Hobolth, O. Andersen, J. Nerup, The Danish Study Group of Diabetes in Childhood

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 682 KB

english, 1993

24

On the pathogenesis of IDDM

J. Nerup, T. Mandrap-Poulsen, S. Helqvist, H. U. Andersen, F. Pociot, J. I. Reimers, B. G. Cuartero, A. E. Karlsen, U. Bjerre, T. Lorenzen

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 1.45 MB

english, 1994

25

Differential interleukin-1 receptor antagonism on pancreatic beta and alpha cells. Studies in rodent and human islets and in normal rats

U. Zumsteg, J. I. Reimers, F. Pociot, L. Mørch, S. Helqvist, M. Brendel, R. Alejandro, T. Mandrup-Poulsen, C. A. Dinarello, J. Nerup

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 994 KB

english, 1993

26

Nicotinamide — biological actions and therapeutic potential in diabetes prevention

F. Pociot, J. I. Reimers, H. U. Andersen

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 419 KB

english, 1993

27

Changes in expression of IL-1β influenced proteins in transplanted islets during development of diabetes in diabetes-prone BB rats

T. Sparre, U. Bjerre Christensen, C. F. Gotfredsen, P. Mose Larsen, S. J. Fey, K. Hjernø, P. Roepstorff, F. Pociot, A. E. Karlsen, J. Nerup

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 378 KB

english, 2004

28

Mutation analysis of suppressor of cytokine signalling 3, a candidate gene in Type 1 diabetes and insulin sensitivity

T. Gylvin, R. Nolsøe, T. Hansen, E. M. D. Nielsen, R. Bergholdt, A. E. Karlsen, N. Billestrup, K. Borch-Johnsen, O. Pedersen, T. Mandrup-Poulsen, J. Nerup, F. Pociot

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 142 KB

english, 2004

29

Suppressor of cytokine signalling (SOCS)-3 protects beta cells against IL-1β-mediated toxicity through inhibition of multiple nuclear factor-κB-regulated proapoptotic pathways

A. E. Karlsen, P. E. Heding, H. Frobøse, S. G. Rønn, M. Kruhøffer, T. F. Ørntoft, M. Darville, D. L. Eizirik, F. Pociot, J. Nerup, T. Mandrup-Poulsen, N. Billestrup

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 315 KB

english, 2004

30

Impact ofIDDM2on disease pathogenesis and progression in children with newly diagnosed type 1 diabetes: reduced insulin antibody titres and preserved beta cell function

L. B. Nielsen, H. B. Mortensen, F. Chiarelli, R. Holl, P. Swift, C. de Beaufort, F. Pociot, P. Hougaard, S. Gammeltoft, M. Knip, L. Hansen, Hvidøre Study Group

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 101 KB

english, 2006

31

To: Biason-Lauber A, Boehm B, Lang-Muritano M et al. (2005) Association of childhood type 1 diabetes mellitus with a variant ofPAX4: possible link to beta cell regenerative capacity. Diabetologia 48:900–905

T. Gylvin, R. Bergholdt, J. Nerup, F. Pociot

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 66 KB

english, 2005

32

Increased prevalence of Down’s syndrome in individuals with type 1 diabetes in Denmark: a nationwide population-based study

R. Bergholdt, S. Eising, J. Nerup, F. Pociot

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 80 KB

english, 2006

33

Predictors of IDDM recurrence risk in offspring of Danish IDDM patients

T. Lorenzen, F. Pociot, L. Stilgren, O. P. Kristiansen, J. Johannesen, P. B. Olsen, A. Walmar, A. Larsen, N. C. Albrechtsen, P. C. Eskildsen, O. O. Andersen, J. Nerup, Danish IDDM Epidemiology and Gen

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 214 KB

english, 1998

34

Mutations in the hepatocyte nuclear factor-1α gene in Caucasian families originally classified as having Type I diabetes

A. M. Møller, L. T. Dalgaard, F. Pociot, J. Nerup, T. Hansen, O. Pedersen

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 59 KB

english, 1998

35

Complete molecular scanning of the human Fas gene: mutational analysis and linkage studies in families with Type I diabetes mellitus

R. L. Nolsøe, O. P. Kristiansen, K. Sangthongpitag, Z. M. Larsen, J. Johannesen, A. E. Karlsen, F. Pociot, J. Nerup, C. F. Verge, T. Mandrup-Poulsen, The Danish Study Group of Diabetes in Childhood an

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 116 KB

english, 2000

36

Polymorphisms in the neurogenin 3 gene (NEUROG) and their relation to altered insulin secretion and diabetes in the Danish Caucasian population

J. N. Jensen, L. Hansen, C. T. Ekstrøm, F. Pociot, J. Nerup, T. Hansen, O. Pedersen

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 57 KB

english, 2001

37

The intercellular adhesion molecule-1 K469E polymorphism in type 1 diabetes

Ole. P. Kristiansen, Runa L. Nolsøe, Heidi Holst, Sine Reker, Zenia M. Larsen, Jesper Johannesen, Jørn Nerup, Flemming Pociot, Thomas Mandrup-Poulsen

Journal:

Année:

2000

Langue:

english

Fichier:

PDF, 62 KB

english, 2000

38

The natural history of anHLAhaplotype and its recombinants

S. D’Alfonso, Iolanda Borelli, Annamaria Dall’Omo, Elisabetta Bolognesi, Jukka Partanen, Antti Levo, Flemming Pociot, Lian Fan, Takeo Juji, Michael Hammond, Roberto Tosi, Patricia Momigliano Richiardi

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 279 KB

english, 1998

39

Genetic markers for glutamic acid decarboxylase do not predict insulin-dependent diabetes mellitus in pairs of affected siblings

Tina Rambrand, Flemming Pociot, Kjersti S. Rønningen, Jørn Nerup, B. K. Michelsen, The Danish Study Group of Diabetes in Childhood

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 96 KB

english, 2007

40

Linkage of type I diabetes to 15q26 (IDDM3) in the Danish population

Mahdi Zamani, Flemming Pociot, Peter Raeymaekers, Jørn Nerup, J.-J. Cassiman

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 41 KB

english, 1996

41

Genetic markers for glutamic acid decarboxylase do not predict insulin-dependent diabetes mellitus in pairs of affected siblings

Tina Rambrand, Flemming Pociot, Kjersti Rønningen, Jørn Nerup, B. K. Michelsen, The Danish Study Group of Diabetes in Childhood

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 144 KB

english, 1997

42

Anaesthesia-induced hyperglycaemia early in life is not predictive for development of diabetes in diabetes-prone BB rats

T. Sparre, A. M. Ejrnaes Sprinkel, U. Bjerre Christensen, A. E. Karlsen, F. Pociot, J. Nerup

Journal:

Acta Diabetologica

Année:

2005

Langue:

english

Fichier:

PDF, 47 KB

english, 2005

43

Quantitative iTRAQ-Based Proteomic Identification of Candidate Biomarkers for Diabetic Nephropathy in Plasma of Type 1 Diabetic Patients

Anne Julie Overgaard, Tine E. Thingholm, Martin R. Larsen, Lise Tarnow, Peter Rossing, James N. McGuire, Flemming Pociot

Journal:

Clinical Proteomics

Année:

2010

Langue:

english

Fichier:

PDF, 386 KB

english, 2010

44

Serum Proteome Pool Changes in Type 2 Diabetic Patients Treated with Anakinra

Mette Koefoed, Claus M. Larsen, Mirjam V. Faulenbach, Allan Vaag, Jan A. Ehses, Marc Y. Donath, James Norton McGuire, Flemming Pociot, Thomas Mandrup-Poulsen

Journal:

Clinical Proteomics

Année:

2010

Langue:

english

Fichier:

PDF, 271 KB

english, 2010

45

Complete mutation scan of the human Fas ligand gene: Linkage studies in Type I diabetes mellitus families

R. L. Nolsøe, O. P. Kristiansen, Z. M. Larsen, J. Johannesen, F. Pociot, T. Mandrup-Poulsen

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 71 KB

english, 2002

46

Complete mutation scanning of the human SEL 1L gene: a candidate gene for type 1 diabetes

Z. M. Larsen, A. D. Angelo, M. Cattaneo, J. Nerup, I. Biunno, M. Zollo, F. Pociot

Journal:

Acta Diabetologica

Année:

2001

Langue:

english

Fichier:

PDF, 38 KB

english, 2001

47

Type 1 diabetes risk analysis on dried blood spot samples from population-based newborns: design and feasibility of an unselected case–control study

Stefanie Eising, Jannet Svensson, Kristin Skogstrand, Anita Nilsson, Kristian Lynch, Paal Skytt Andersen, Åke Lernmark, David M. Hougaard, Flemming Pociot, Bent Nørgaard-Pedersen, Jørn Nerup

Journal:

Paediatric and Perinatal Epidemiology

Année:

2007

Langue:

english

Fichier:

PDF, 205 KB

english, 2007

48

Monocyte Function in IDDM Patients and Healthy Individuals

J. MØLVIG, F. POCIOT, L. BÆK, H. WORSAAE, L. DALL WOGENSEN, P. CHRISTENSEN, L. STAUB-NIELSEN, T. MANDRUP-POULSEN, K. MANOGUE, J. NERUP

Journal:

Scandinavian Journal of Immunology

Année:

1990

Langue:

english

Fichier:

PDF, 1.08 MB

english, 1990

49

Dietary Supplementation with co-3-Polyunsaturated Fatty Acids Decreases Mononuclear Cell Proliferation and Interleukin-1β Content but not Monokine Secretion in Healthy and Insulin-Dependent Diabetic Individuals

J. MØLVIG, F. POCIOT, H. WORSAAE, L. D. WOGENSEN, L. BAEK, P. CHRISTENSEN, T. MANDRUP-POULSEN, K. ANDERSEN, P. MADSEN, J. DYERBERG, J. NERUP

Journal:

Scandinavian Journal of Immunology

Année:

1991

Langue:

english

Fichier:

PDF, 701 KB

english, 1991

50

A Tumour Necrosis Factor Beta Gene Polymorphism in Relation to Monokine Secretion and Insulin-Dependent Diabetes Mellitus

F POCIOT, J. Mølvig, L. WOGENSEN, H. WORSAAE, H. DALBØGE, L. BAEK, J. NERUP

Journal:

Scandinavian Journal of Immunology

Année:

1991

Langue:

english

Fichier:

PDF, 3.74 MB

english, 1991